Carcinogens are substances that can potentially cause cancer. While exposure to these chemicals doesn’t guarantee that you’ll develop cancer, it’s essential to be aware of them. Here are some common carcinogens you might encounter in daily life. Tobacco: At least 70 chemicals in tobacco are known to cause cancer by damaging your DNA. Whether you’re a smoker or exposed to secondhand smoke, the risk remains high. Even light smoking increases your chances of developing cancer. If you smoke, consider discussing ways to quit with your doctor. Radon: This gas occurs naturally but can become harmful when it accumulates indoors. Breathing in radon can lead to lung cancer, making it the top cause of lung cancer in nonsmokers. Special tests can check radon levels in your home. Asbestos: Tiny, tough asbestos fibers strengthen products like roof shingles and car parts. However, if these fibers break free and you inhale them, they can lodge in your lungs. Studies confirm that asbestos is a carcinogen. If you encounter it at work, use protective gear. For home situations, consult an expert if removal is necessary. Acrylamide: Found in crispy, browned foods (like roasted potatoes), acrylamide has been linked to cancer. Studies on rats suggest that humans might also be affected. To reduce exposure, bake, roast, fry, or toast foods until they’re tan rather than golden or deep brown. Formaldehyde: Used in various household products (from plywood to fabrics), formaldehyde has been shown to cause cancer in lab rats and people exposed to it at work. Before buying wood products or furniture, check if they contain formaldehyde. Proper ventilation and humidity control can help minimize exposure. Ultraviolet Rays: Whether from the sun or tanning beds, UV rays get absorbed into your skin and damage cells. Prolonged exposure increases the risk of skin cancer. Remember that minimizing exposure to these carcinogens is crucial for maintaining good health. Consult with healthcare professionals and take preventive measures whenever possible. Your New Health AI Assistant Make Informed Decisions for Your Health Your health is important and your most valuable asset, but knowing what is best for you can be hard and a life-saving decision. There are so many factors that affect your well-being, such as your genetics, your lifestyle, your environment, and your preferences. That's why you need the iScript personal lifestyle assistant, a smart tool that helps you make the right choices for your health based on your personal needs. The iScript personal lifestyle assistant analyzes your data and gives you personalized recommendations for nutrition, exercise, supplements, and more. It takes the guesswork out of what your body needs and helps you achieve optimum health and vitality. Whether you want to lose weight, gain muscle, improve your mood, or prevent diseases, the iScript personal lifestyle assistant can guide you to your goals. Get All the Health Tools You Need in a Single Platform Reapian Medical Technologies | reapian.com | Stellenbosch, SA

The exploration of biochemical imbalances through biomarkers is a significant advancement in understanding metabolic health. Techniques like 360-data epigenetics and Health-iQ represent a fusion of biological data collection and computational analysis, where dry blood spots and fecal samples serve as sources for extracting vital health information. The integration of machine learning algorithms into medical technology, such as the iScript Premium BioWellnessPlus** and the 360 Health Protector Programs, allows for the identification of health pathways and the formulation of personalized interventions to address these imbalances. This approach not only enhances the precision of health assessments but also empowers registered health practitioners with actionable insights derived from complex data analyses. By accessing comprehensive reports, healthcare providers can tailor their recommendations and interventions to the unique needs of their clients, marking a transformative step towards personalized medicine and optimized health outcomes. The convergence of epigenetics, machine learning, and clinical practice heralds a new era of data-informed healthcare strategies that prioritize individualized client care. The iScript Health-iQ BioWellnessPlus** health evaluation is designed to gather comprehensive data on an individual's health-related factors. By participating, you contribute valuable information that can influence the personalization of your healthcare. The survey covers a range of topics from basic demographics to detailed lifestyle habits, aiming to tailor the iScript services to your unique profile. The free version offers a glimpse into the iScript ecosystem, while the premium version expands the offerings with advanced tests and screenings. These include DBS Blood Tests and screenings for telomere length and specific cancers, which are crucial for early detection and prevention strategies. The monthly PharmaX Formulary and the personalized iScript BioWellnessPlus** formula are additional benefits that adapt based on your test outcomes, ensuring a proactive approach to maintaining colon and pancreas health, both of which are essential for long-term well-being. The journey to longevity is fascinating, and it turns out that a healthy gut and pancreas play a pivotal role in this quest. A thriving gut microbiome, rich in diverse bacteria, is linked to numerous health benefits, including a robust immune system, efficient nutrient absorption, and a reduced risk of chronic diseases. It's like having a bustling city within you, where each microbe has a job that contributes to your overall well-being. Harvard Health highlights the importance of nurturing these beneficial microbes through a balanced diet rich in fiber from fruits, vegetables, legumes, and whole grains. Exercise, too, plays a role in promoting gut health, possibly by altering the rate at which food moves through the gut or by reducing inflammation. Moreover, studies suggest that a diverse gut microbiome is a common trait among centenarians, hinting at its potential influence on a long and healthy life. The gut microbiome's ability to produce beneficial metabolites and fight inflammation is a testament to its power in our health and longevity. It's not just about adding years to life, but also life to those years, ensuring that we can enjoy our later years with vitality and happiness. So, embracing a lifestyle that supports gut health could be a key to unlocking a longer, more fulfilling life. Remember, taking care of your gut is not just a health strategy; it's an investment in a vibrant future. Reapian Medical Technologies | Stellenbosch, SA | reapian.com

Lactobacillus Sporogenes is also known as Weizmannia coagulans, a type of probiotic bacteria. Probiotics are live microorganisms that can confer health benefits to the host when consumed in adequate amounts. Some of the major benefits of Weizmannia coagulans compared to other probiotics are: It is a spore-forming bacterium, which means it can survive harsh conditions such as high temperature, acidity, and bile salts, and reach the intestine alive. It produces lactic acid, which can lower the pH of the intestine and inhibit the growth of harmful bacteria. It can modulate the intestinal microbiota and host immunity and has shown positive effects on gastrointestinal conditions, such as irritable bowel syndrome, constipation, diarrhea, hepatic encephalopathy, and ulcerative colitis. It can also improve the quality of life and metabolic parameters of overweight, obese, diabetic, and menopausal patients. PROBIGUARD** is formulated with Lactobacillus Sporogenes. PROBIGUARD™ is an advanced probiotic immune modulator complex, designed to help restore and support a healthy immune system. Microbiotics, also known as probiotics, play a significant role in controlling high blood pressure. Here’s how: Gut Health and Inflammation: An imbalance in gut bacteria can lead to inflammation, which has been linked to elevated blood pressure. Probiotics help maintain balance in the gut, reduce inflammation, and thereby help with blood pressure. Probiotic Strains: Certain strains of probiotics, such as Bifidobacterium and Lactobacillus, have been found to reduce blood pressure. Diet and Lifestyle: Probiotics can be altered or potentially corrected in response to various factors, such as diet. A healthful diet, such as the Mediterranean diet, positively influences the gut microbiome and enhances the number of beneficial bacteria in the gut. Cholesterol Levels: High levels of cholesterol can contribute to the build-up of plaques in your arteries. By reducing these and lowering your risk for plaques, probiotics keep your arteries healthy and your blood pressure regulated. Please note that while probiotics show promise in managing high blood pressure, more research is needed to fully understand their role. Always consult with a healthcare professional before starting any new treatment regimen. Managing high blood pressure is a crucial aspect of maintaining overall health, especially for those with a personal or family history of hypertension. The iScript BioWellnessPlus Health-iQ Report offers a comprehensive analysis tailored to individual needs, providing insights into lifestyle choices that can influence blood pressure control. This personalized report, available at no cost, serves as a valuable tool in guiding individuals towards healthier habits and informed decisions about their well-being. For more information on how to access this free resource and take a proactive step in managing your health, follow the steps below: Reapian Medical Technologies | reapian.com | Stellenbosch, SA

Including colon and pancreas health tests in a comprehensive health analysis is crucial for several reasons: Pancreas Health Assessment: The pancreas is a vital organ in the digestive system. It plays a dual role by releasing digestive enzymes to break down proteins and fats, as well as hormones to regulate blood sugar levels. Pancreas tests help evaluate the health of the pancreas and identify potential issues such as pancreatitis (inflammation of the pancreas) and pancreatic cancer. These tests include: Blood Tests: The amylase test checks for elevated levels of the amylase enzyme (which aids in carbohydrate digestion), while the lipase test assesses the lipase enzyme (involved in fat digestion) Function Tests: These evaluate the chemical functioning of the pancreas, measuring enzyme levels in blood or stool samples. They provide insights into how well the pancreas is performing its functions Imaging Tests: Techniques like CT scans, ultrasounds, and MRIs allow visualization of the pancreas, detecting inflammation, swelling, cysts, gallstones, and tumors Colon Health Considerations: The colon, also known as the large intestine, plays a crucial role in digestion, nutrient absorption, and waste elimination. Including colon health tests help detect conditions such as colorectal cancer, inflammatory bowel disease, and polyps. Common colon health tests include: Colonoscopy: A direct examination of the colon using a flexible tube with a camera. Fecal Occult Blood Test (FOBT): Detects hidden blood in stool, which may indicate bleeding from the colon. Sigmoidoscopy: Similar to a colonoscopy but examines only the lower part of the colon. Virtual Colonoscopy (CT Colonography): Uses CT scans to visualize the colon. Stool DNA Test: Screens for genetic changes associated with colorectal cancer. Overall Health Implications: A poorly functioning pancreas or colon can lead to various digestive problems, affecting overall well-being. Early detection of issues allows for timely intervention and better management. Abnormal results from these tests may indicate underlying diseases, prompting further investigation and treatment. In summary, including colon and pancreas health assessments in a broader health analysis ensures a comprehensive evaluation, early detection of potential problems, and informed decision-making regarding overall health and well-being. CREATE A FREE MEMBER ACCOUNT TODAY AND STAY UP TO DATE WITH DEVELOPMENTS FOR COLON AND PANCREAS HEALTH-iQ PLAN TESTS The BioWellnessPlus* Health-iQ Plans Non-Invasive Colon and Pancreas Health screening tests The iScript Roadmap to lower future health and Medical Expenses Reapian Medical Technologies | reapian.com | Stellenbosch, South Africa

The gut-brain connection is a sophisticated system that involves the interaction of various elements, such as nerves, hormones, neurotransmitters, gut microbiota, and immune components, between the digestive tract and the central nervous system. This system enables the gut to affect the brain’s functions, such as mood, cognition, and behavior, and also allows the brain to influence the gut’s activities. The gut-brain connection is important for maintaining both gut health and brain health. Some of the ways that gut health can affect brain health are: Gut bacteria can produce neurotransmitters, such as serotonin, dopamine, and gamma-aminobutyric acid (GABA), that regulate mood, memory, and learning. These neurotransmitters can travel from the gut to the brain through the bloodstream or the vagus nerve, a major nerve that connects the brain and the gut. Gut bacteria can also produce short-chain fatty acids (SCFAs), such as butyrate, propionate, and acetate, that have anti-inflammatory and neuroprotective effects. SCFAs can modulate the activity of immune cells and glial cells in the brain, which are involved in neuroinflammation and neurodegeneration. Gut bacteria can influence the production and secretion of hormones, such as cortisol, melatonin, and oxytocin, that affect the stress response, the sleep cycle, and the social behavior of the brain. Hormones can also affect the composition and diversity of the gut microbiota, creating a feedback loop between the gut and the brain. Gut bacteria can alter the permeability of the intestinal barrier, which can lead to increased levels of endotoxins, such as lipopolysaccharide (LPS), in the blood. LPS can trigger systemic inflammation and activate the immune system, which can impair the function and structure of the brain. Gut bacteria can interact with dietary components, such as polyphenols, prebiotics, and probiotics, that can modulate the gut-brain axis and have beneficial effects on brain health. For example, polyphenols can enhance the growth of beneficial bacteria and inhibit the growth of harmful bacteria, prebiotics can stimulate the production of SCFAs and neurotransmitters, and probiotics can improve the intestinal barrier and reduce inflammation. As you can see, the brain and the gut are closely connected, and their health influences each other. A balanced and diverse gut microbiota is essential for optimal brain function, and can be supported by a healthy diet, avoiding antibiotics and stress, and taking supplements if needed. REFERENCES 1: The gut-brain connection - Harvard Health 2: What’s the connection between the gut and brain health? - Harvard Health 3: The gut brain axis: What it is and how to improve it - Medical News Today Reapian Medical Technologies (Pty)Ltd | Stellenbosch, SA | reapian.com

Lactobacillus sporogenes is also known as Weizmannia coagulans, a type of probiotic bacteria. Probiotics are live microorganisms that can confer health benefits to the host when consumed in adequate amounts. Some of the major benefits of Weizmannia coagulans compared to other probiotics are: It is a spore-forming bacterium, which means it can survive harsh conditions such as high temperature, acidity, and bile salts, and reach the intestine alive. It produces lactic acid, which can lower the pH of the intestine and inhibit the growth of harmful bacteria. It can modulate the intestinal microbiota and host immunity and has shown positive effects on gastrointestinal conditions, such as irritable bowel syndrome, constipation, diarrhea, hepatic encephalopathy, and ulcerative colitis. It can also improve the quality of life and metabolic parameters of overweight, obese, diabetic, and menopausal patients. However, the effectiveness of Weizmannia coagulans may depend on the strain, dose, and disease-specific factors. PROBIGUARD IS FORMULATED WITH WEIZMANNIA COAGULANS View the full list of ingredients on the below link: Reapian Medical Technologies (Pty)Ltd | Stellenbosch, SA | reapian.com

Nausea, loss of appetite, and frequent trips to the bathroom; these are some of the common signs of stomach problems. Your stomach may be upset for various reasons, such as food poisoning, a stomach virus, or a chronic condition. If you have a persistent or severe stomach problem, you should not ignore it. It may indicate a more serious issue that requires medical attention. Here are 15 symptoms that suggest your gut is not working well: FREQUENT DIARRHEA. Frequent diarrhea is a condition that causes you to have loose, watery stools more often than usual. It can be acute, lasting for a few days, or chronic, lasting for weeks or months. Some possible causes of chronic diarrhea are irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), or celiac disease. These are serious conditions that require medical attention and treatment. You can use some over-the-counter medicine to ease the symptoms of acute diarrhea, but if it does not go away after two days, or if you become dehydrated, you should see a doctor as soon as possible. BLOOD IN STOOL. Seeing blood in your stool after using the bathroom can be scary and worrisome. There are many possible causes of this symptom, some of which are mild and others that are more serious. The colour of the blood can help you identify where the bleeding is coming from. If you have blood in your stool, it could be a sign of hemorrhoids, which are easy to treat, or colorectal cancer (CRC), which is a serious condition. The best thing to do is to talk to your doctor as soon as possible to find out the cause and get the right treatment. SEVERE CRAMPS AFTER EATING. Eating is usually a pleasurable experience as well as a way to fuel our bodies. However, if you find that you have severe cramps after consuming food it can definitely take away from enjoying your meals. The occasional belly ache is normal, but if the pain persists and happens nearly every time you eat a meal, it might be signalling that something is wrong. Sometimes the pain is caused by eating too much, while other times it could stem from a food intolerance or allergy. If your pain is severe, it could be a good time to talk to your doctor and rule out IBS or IBD. CHRONIC CONSTIPATION Constipation is indeed a common gastrointestinal issue that can be influenced by various factors such as medication, lack of physical activity, a low-fiber diet, and conditions like Irritable Bowel Syndrome (IBS). Lifestyle modifications often play a crucial role in managing this condition. Regular exercise, a balanced diet rich in fiber, and staying hydrated can significantly improve bowel regularity. However, persistent constipation may require medical attention to identify any underlying issues. It’s always recommended to consult with a healthcare professional for a comprehensive evaluation and appropriate treatment plan. FREQUENT HEARTBURN. Heartburn, characterized by a burning sensation in the chest that may travel up to the throat, can indeed be a symptom of Gastroesophageal Reflux Disease (GERD). This condition is often associated with other symptoms such as coughing, hiccups, bad breath, and bloating. Certain foods, particularly those that are fatty or acidic, can trigger heartburn. Frequent heartburn is not something to be ignored as it could indicate GERD. If you’re experiencing severe symptoms or find yourself relying on over-the-counter heartburn medications more than twice a week, it’s recommended to seek medical attention. A healthcare professional can provide a proper diagnosis and guide you towards an appropriate treatment plan. It’s always important to prioritize your health and address any concerns promptly. DIFFICULTY SWALLOWING. Dysphagia, or difficulty swallowing, is a condition that affects many people, with approximately 15 million Americans experiencing it. While it can sometimes resolve on its own, persistent dysphagia could be indicative of more serious conditions such as Gastroesophageal Reflux Disease (GERD), heartburn, or even esophageal cancer. Experiencing pain, choking, or coughing when swallowing are signs that medical attention may be necessary. It’s always advisable to consult with a healthcare professional if you have any concerns about your health. They can provide a proper diagnosis and guide you towards an appropriate treatment plan. Your health should always be a priority, and any persistent or concerning symptoms should be evaluated by a medical professional. LOSS OF APPETITE. Anorexia, or a prolonged loss of appetite, can be a symptom of various health conditions. Temporary loss of appetite can indeed be due to common illnesses such as viral or bacterial infections. However, if the condition persists, it could indicate more serious health issues. Digestive conditions, such as gastroenteritis or peptic ulcers, can lead to a decreased desire to eat. Inflammatory conditions like Crohn’s disease can also cause anorexia due to the discomfort and pain associated with eating. In some cases, persistent anorexia could be a symptom of stomach cancer or other types of cancer, as these diseases can significantly impact appetite and digestion. It’s crucial to consult a healthcare professional if you or someone else experiences a prolonged loss of appetite. They can provide a proper diagnosis and recommend an appropriate treatment plan. Remember, early detection and treatment of any health issue can significantly improve the prognosis. Your health should always be your top priority. UNEXPLAINED WEIGHT LOSS. Unexplained weight loss can be a symptom of various conditions, both physical and psychological. It’s important to consult a healthcare professional if you’re experiencing this, as they can help identify the underlying cause and suggest appropriate treatments or interventions. Remember, it’s crucial to take care of both your physical and mental health. If stress is a contributing factor, finding healthy ways to manage it, such as through exercise, meditation, or talking to a professional, can be beneficial. The cause of unexplained weight loss could be anything from stressful life experiences, such as divorce or losing a job, to a more serious health condition. Some conditions that cause weight loss are depression and anxiety, IBS, celiac disease, or even cancer. SUDDEN ABDOMINAL PAIN. Abdominal pain can have a wide range of causes, from minor issues like gas or stomach cramps to more serious conditions like appendicitis. Home remedies, such as sipping clear liquids and avoiding solid foods, can be helpful for milder cases. However, it’s crucial to seek immediate medical attention if the pain is severe, accompanied by other symptoms like chest, neck, or shoulder pain, inability to pass stool, especially with vomiting, or if the pain persists for more than 24 hours. FEELING FULL AFTER EATING A SMALL PORTION. The condition of early satiety and its potential cause, is called gastroparesis. This condition can indeed lead to a feeling of fullness after eating only a small amount of food. It’s important to note that other symptoms such as heartburn, an upset stomach, and vomiting undigested food can accompany this condition. As you mentioned, managing diet, controlling blood sugar, and taking prescribed medications are common treatments. However, it’s crucial to consult with a healthcare professional if one experiences these symptoms frequently. They can provide a proper diagnosis and treatment plan. Health is a serious matter, and it’s always better to seek professional advice when in doubt. SWOLLEN ABDOMEN. Also called abdominal distension. Discomfort and swelling in the midsection can be due to various factors, including overeating, gas, Irritable Bowel Syndrome (IBS), lactose intolerance, or even a partial bowel blockage. It’s crucial to note that if the swelling worsens, is accompanied by a high fever, or if the abdomen is tender to touch, immediate medical attention is necessary. These symptoms could indicate a serious condition such as fluid buildup in the abdominal cavity, also known as ascites. Health is a serious matter, and it’s always better to seek professional advice when in doubt. ANEMIA. Iron-deficiency anemia, a common condition where the body lacks sufficient healthy red blood cells to carry adequate oxygen to the body’s tissues. Anemia can be associated with gastrointestinal issues, and a significant proportion of patients with Inflammatory Bowel Disease (IBD) may suffer from anemia. The symptoms include fatigue, headaches, and loss of appetite, are typical of anemia and should not be ignored. It’s crucial to seek medical help if these symptoms persist. Treatments such as blood transfusions, corticosteroids, and iron supplements, are commonly used to manage anemia. However, the specific treatment plan would depend on the underlying cause and severity of the anemia, and should always be guided by a healthcare professional. WEAKNESS AND FATIQUE. Chronic fatigue can be a symptom of various health conditions, not just physical but also mental. It’s crucial to consult a healthcare professional if one experiences persistent tiredness, as it could indicate serious underlying issues like liver failure, diabetes, depression, or even Irritable Bowel Syndrome (IBS). A well-balanced diet can indeed help manage these symptoms, but it’s not a substitute for professional medical advice and treatment. FREQUENT VOMITING. Persistent nausea and vomiting can be a sign of serious health conditions. While it’s common for these symptoms to occur due to a bacterial or viral infection, they can also indicate conditions like appendicitis, cyclic vomiting syndrome, or achalasia. It’s crucial to seek medical attention if these symptoms persist. SKIN CONDITIONS. The connection between gut health and skin conditions is increasingly recognized in medical research. It’s estimated that 25% to 30% of individuals with Crohn’s disease also experience skin conditions. Conditions like eczema, psoriasis, and rosacea can often be managed with dietary changes, hydration, and prescribed medication. Persistent skin issues can indeed be a sign of underlying health concerns, so it’s always advisable to consult a healthcare professional for persistent symptoms. PROBIGUARD with a powerful trusted combination of nutrients to assist with gut and general health. TRUNAD Support lifelong longevity and daily vitality with this unique NAD+ booster. Reapian Medical Technologies (Pty) Ltd | Stellenbosch, South Africa | reapian.com

How AI Can Help You Choose the Right Supplements for Your Health There are several ways in which AI can help you make informed decisions about your health and supplements. One such example is iScript iAI Personal Assistant, a free Reapian Medical Technologies AI Framework service. It provides a comprehensive database of supplements, drugs, and 59,096 possible interactions between them. You can use this tool to discover supplement-drug interactions and explore related research that will take into account your current lifestyle choices, personal health challenges, and family history. The development of AI-powered tools that allow researchers to process insights into thousands of diseases, gene associations, and ingredient interactions, to develop productive nutraceutical solutions. These tools can help researchers develop scientifically sound supplements at speed. What You Need to Know About AI and Supplements Before You Buy Certain supplements can interact with each other, leading to decreased effectiveness, increased risk of side effects, or potential harm to your health. For example, taking calcium and iron supplements together can reduce the absorption of iron. Similarly, taking vitamin C and iron supplements together can enhance iron absorption, which can be a good thing. However, if taken in excess, it can lead to iron toxicity. Discover the best supplements and health or fitness recommendations for your health goals with the iScript Health-iQ report. This free report will give you personalized recommendations based on your health profile and also offer you valuable insights and suggestions on how to enhance your wellness and vitality. Reapian Medical Technologies | Stellenbosch, SA | reapian.com

Predictive Analysis: AI can predict health risks years in advance. For example, researchers at the University of Oxford have used AI to improve the accuracy of cardiac CT scans, potentially predicting heart attack risks up to 10 years into the future. Disease Diagnosis and Treatment: AI is being used to diagnose diseases, create personalized treatment plans, and even predict patient survival rates. For instance, MIT’s AI tool can predict lung cancer risk up to six years in advance. Improving Healthcare Systems: AI and machine learning are helping to alleviate stresses on global healthcare systems, from speeding up drug development to reducing healthcare workers’ administrative loads. Generative AI: This branch of AI has been thrust into the limelight following the release of ChatGPT in November 2022 and OpenAI. Generative AI could add trillions of dollars in value to the global economy, enabling labor productivity growth. These advancements in AI are not only helping healthcare workers save time, but also lives1. As AI continues to evolve, it’s expected to bring even more groundbreaking changes to the healthcare industry. Reapian Medical is a state-of-the-art medical technology company that specializes in developing remote health assessment and diagnostic solutions. Our mission is to provide the best in medical technology to ensure that our customers have access to quality health care. By integrating the latest scientific advances and technologies into our products and services, we are able to provide our customers with a comprehensive solution for remote diagnosis and treatment. We strive to make health management and medical care more accessible and reliable for people everywhere. WELCOME TO iScript Artificial Intelligence Our iScript Personal Assistant (iScript AI or iAI) helps you achieve your best health and vitality by customizing your wellness plan. After you fill out the iScript Lifestyle survey, you will get your detailed iScript report. This report is based on your specific needs and gives you guidance on how to reach your health goals and optimal vitality. The first step to join The 360 Health Protector Program is to sign up and complete the iScript Health-iQ survey. This way, you can learn about your health status and how to improve it. This program also helps you prevent disease and lower your medical insurance costs by keeping you informed and flexible. This is the smart and personalized way to take care of your health. Reapian Medical Technologies | Stellenbosch, SA | reapian.com

Reapian Medical's XSPN BCAA Amino Boost supplement is not just for athletes, but for anyone who wants to improve their health and wellness. This supplement provides essential amino acids and 5-MTHF that support muscle growth, recovery, and energy. Whether you are a fitness enthusiast, a busy professional, or a senior citizen, you can benefit from this amazing product. Reapian Sport XSPN BCAA Amino Boost contains 5-Methyltetrahydrofolate (5-MTHF) - the methylated form of folate, a B vitamin (B9). It plays a crucial role in various bodily functions. Here are some of the benefits of 5-MTHF: Healthy Conception and Fetal Development: Both folate and folic acid—its synthetic form—are essential for healthy conception, fetal development, and prevention of neural tube defects. DNA Formation and Cell Growth: It is vital for DNA formation, cell growth, and other bodily functions. Heart Health: Certain variations in the MTHFR gene can increase the risk of heart problems in men. Therefore, improved heart health is one of the benefits of 5-MTHF. Balanced Iron Levels: 5-MTHF can help balance iron levels. Cognitive Function: It can enhance cognitive function. Energy Levels: It can increase energy levels. Immune System: It can boost the immune system. Reducing Homocysteine Levels: Therapeutically, 5-MTHF is instrumental in reducing homocysteine levels. Improving Vascular Endothelial Function: It helps in improving vascular endothelial function. However, the benefits of 5-MTHF can be profound if you have specific gene mutations, although you might not feel or see changes. If you’re considering supplementation, it’s worth discussing with your healthcare provider. The MTHFR gene mutation refers to changes in the methylenetetrahydrofolate reductase (MTHFR) gene, which is involved in the metabolism of folate (vitamin B9). Symptoms produced directly by the MTHFR gene mutation are uncommon1. However, certain health conditions have been associated with MTHFR gene variants. Here are some potential symptoms and related conditions: Hyperhomocysteinemia: Abnormally high levels of homocysteine in the blood or urine. Cardiovascular Diseases: This may include coronary heart disease, blood clots, stroke, and heart attack. Birth Abnormalities: This may include neural tube defects or conditions such as microcephaly, in which the head is smaller than expected at birth. Dementia: Symptoms of cognitive decline, such as memory loss, confusion, and mood changes. Mental Health Conditions: People with the MTHFR gene variant may be at higher risk of depression. Drug-Induced Toxicity: People with the MTHFR gene variant may have a higher risk of toxicity from medication affecting folate homeostasis, such as methotrexate (MTX). Peripheral Neuropathy: This is a neurological condition that damages the nerves. Fatigue, Headaches, and Difficulty Concentrating: These are common symptoms. Depression, Anxiety, Bipolar Disorder, Chronic Pain, Nerve Pain, Fertility Issues: These symptoms are commonly associated with MTHFR, although they are anecdotal. It’s important to note that symptoms vary among individuals and depend on the type of mutation someone has. People may not know they have an MTHFR mutation unless they experience severe symptoms or undergo genetic testing2. If you suspect you have an MTHFR mutation, it’s essential to consult a healthcare provider for proper diagnosis and management. SUMMARY Your health is important, but it can be hard to know what is best for you. There are so many factors that affect your well-being, such as your genetics, your lifestyle, your environment, and your preferences. That's why you need the iScript personal lifestyle assistant, a smart tool that helps you make the right choices for your health based on your personal needs. The iScript personal lifestyle assistant analyzes your data and gives you personalized recommendations for nutrition, exercise, supplements, and more. It takes the guesswork out of what your body really needs and helps you achieve optimum health and vitality. Whether you want to lose weight, gain muscle, improve your mood, or prevent diseases, the iScript personal lifestyle assistant can guide you to your goals. Reapian Medical Technologies | Stellenbosch, SA | reapian.com

Recent scientific studies have explored the relationship between pet ownership and mental health. A study conducted in the United States during the COVID-19 pandemic found that dog owners reported having significantly more social support available to them compared to potential dog owners, and their depression scores were also lower, compared to potential dog owners. However, a survey conducted by the University of York revealed that living with an animal did not improve well-being or reduce depression, anxiety, or feelings of loneliness for owners with serious mental illnesses, such as bipolar disorder or schizophrenia, compared to those who live without an animal. It is important to note that the relationship between pet ownership and mental health is complex and can vary depending on the individual and the type of pet. While some studies suggest that owning a pet can have positive effects on mental health, others have found no significant correlation. If you are considering getting a pet, it is important to weigh the potential benefits and drawbacks and make an informed decision that is right for you. THE iSCRIPT HEALTH-iQ REPORT Our iScript Health-iQ Report explores the profound influence pet ownership exerts on mental well-being. This report elucidates the intricate dynamics between human-animal companionship and its implications for mental health, offering valuable insights for both professionals in the field and pet owners alike. Our iScript iAI has also been trained on the effects that pets may have on allergies and related conditions. like eczema and other skin conditions, as well as providing possible solutions. PROBIGUARD Powerful Health Booster BUY 2 AND GET 1 FREE Scientific References 1: Martin F, Bachert KE, Snow L, Tu H-W, Belahbib J, Lyn SA (2021) Depression, anxiety, and happiness in dog owners and potential dog owners during the COVID-19 pandemic in the United States. PLoS ONE 16 (12): e0260676. 2: University of York. (2023, July 14). Owning a pet does not reduce symptoms of severe mental illness, a study shows. Medical Xpress. Reapian Medical Technolgies (Pty) Ltd | Stellenbosch, SA | reapian.com

Artificial Intelligence (AI) has the potential to revolutionize healthcare and improve the quality of life for people around the world. According to a report by the Global Burden of Disease Cancer Collaboration, AI can help in early detection and diagnosis of diseases, personalized treatment plans, and drug discovery. Here are some ways in which AI can help improve quality of life in 2024: Personalized medicine: AI can help doctors create personalized treatment plans based on a patient’s unique genetic makeup, lifestyle, and medical history. This can lead to more effective treatments and better outcomes for patients. Early detection and diagnosis: AI can help in early detection and diagnosis of diseases, such as cancer, by analyzing large amounts of data from medical images, electronic health records, and other sources. Drug discovery: AI can help in the discovery of new drugs and treatments by analyzing large amounts of data and identifying patterns that humans might miss. Remote monitoring: AI can help in remote monitoring of patients, allowing doctors to keep track of their health and intervene if necessary. Improved patient experience: AI can help in improving the patient experience by reducing wait times, streamlining administrative tasks, and providing personalized care. Reduced healthcare costs: AI can help in reducing healthcare costs by improving efficiency, reducing errors, and optimizing resource allocation. Remember, The iScript iAI is not a replacement for human doctors, but rather a tool that can help them provide better care. By leveraging the power of AI, we can improve healthcare outcomes and enhance the quality of life for people around the world. CANCER CASES ARE RISING According to a study by the Global Burden of Disease Cancer Collaboration, the rise in cancer cases is mainly due to population aging and growth, along with changes in age-specific cancer rates. The World Health Organization (WHO) indicates that the most common types of cancers diagnosed in 2020 were: breast cancer, lung cancer, colon and rectal cancer, prostate cancer, and non-melanoma skin cancer. While modern science has made significant strides in cancer prevention and treatment strategies, there are still many factors that contribute to the rise in cancer cases. For instance, poor diets, alcohol and tobacco use, physical inactivity, and obesity are likely to be among the factors. Additionally, the COVID-19 pandemic has had an impact on cancer prevention, diagnosis, and treatment. It is important to note that despite the increase in cancer cases, the overall cancer mortality rate has been steadily decreasing over the last few decades. This is due to factors such as a reduction in the number of people who smoke and the addition of chemotherapy treatment after surgery for breast and colon cancer. Remember, cancer is a complex disease, and there are many factors that contribute to its incidence. However, by making healthy lifestyle choices and getting regular check-ups, you can reduce your risk of developing cancer and improve your overall health. Reapian Medical Technologies | Stellenbosch South Africa | reapian.com Improving Health Services Delivery Through Remote Health Asset Management